Ityuwa ye-ATP disodium CAS 987-65-5

I-CAS:987-65-5

Ubunyulu:99%

Ifomula yeMolekyuli:C10H17N5NaO13P3

Ubunzima beemolekyuli:531.18

I-EINECS:213-579-1

Ixesha Lokugcina:iminyaka eyi-2

Izithethantonye:I-ADENOSINETRIPHOSPHATEDIUM; I-ADENOSINETRIPHOSPHATE,ITYALOYISHI; I-ADENYLPYROPHOSPHORICACIDDISODIUMSALT; I-ADENOSINE-5′-TRIPHOSPHATEI-HYDRATEDISODIUMSALT; I-ADENOSINE-5′-TRIPHOSPHATENA2-ITYAWU; I-ADENOSINE-5′-TRIPHOSPHATENA,ITYAWU; I-ADENOSINE-5′-TRIPHOSPHORICACIDDISODIUMSALT; I-ADENOSINE5′-TRIPHOSPHORICACIDDISODIUMSALT

Shiya umyalezo wakho

Iinkcukacha zeMveliso

Khuphela

Iithegi zeMveliso

Yintoni i-ATP disodium salt CAS 987-65-5?

Ityuwa ye-ATP disodium yi-metabolite ye-adenosine, i-nucleoside triphosphate esebenza ngeendlela ezininzi esetyenziswa njenge-coenzyme yokudluliselwa kwamandla ngaphakathi kweeseli kwiiseli. Ithutha amandla eekhemikhali ngaphakathi kweeseli ukuze kwenziwe imetabolism. Ityuwa ye-ATP disodium isetyenziselwa ukwenza ii-ribose-modified deoxyadenosine diphosphate analogs njenge-P2Y1 receptor ligands.

Inkcazo

Inkangeleko	Umgubo omhlophe okanye umgubo omhlophe okanye umgubo wekristale, ofana ne-hygroscopic.
Ubungakanani beenxalenye	> 95% idlula kwi-80 mesh.
pH	2.5～3.5
Ukunyibilika	Iyanyibilika emanzini; ayinyibiliki kwi-ethanol kunye ne-ether.
I-Oder	Akukho Oder
Umthamo wamanzi	6.0%~12.0%
I-chloride	≤0.05%
Ityuwa yesinyithi	≤0.001%
Iintsimbi ezinzima	≤0.001%
Inkokeli	≤2.0ppm
I-Arsenic	≤1.0ppm

Isicelo

1. Ukusetyenziswa kophando lwezemizi-mveliso nolwesayensi
(1) Izinto zokuhlobisa: xa zongezwa kwiimveliso zokhathalelo lolusu ezilwa nokwaluphala, zinokuphucula ukuthamba kolusu kunye nokukhazimla ngokuvuselela imetabolism yamandla eseli.
(2) Izongezo zokutya: zisetyenziswa njengesithako sokondla kwiziselo zemidlalo nasekutyeni okusebenzayo ukuze kubuyiselwe amandla ngokukhawuleza.
2. Iindawo zonyango lwezonyango
(1) Izifo zenkqubo yentliziyo: zisetyenziselwa ukusilela kwentliziyo, i-myocarditis, i-myocardial infarction kunye ne-cerebral arteriosclerosis, njl.njl., ngokuphucula imetabolism yamandla e-myocardial kunye nokwandisa imithambo yentliziyo (ukwandisa ukuhamba kwegazi malunga ne-30%), ukunciphisa iimpawu ze-myocardial ischemia. Umzekelo, kwizigulane ezine-acute myocardial infarction, i-ATP disodium inokunciphisa ixesha lokuwa kwe-ST segment kwaye inciphise ixabiso eliphezulu le-spectrum ye-myocardial enzyme.
(2) Izifo zenkqubo yemithambo-luvo: unyango oluncedisayo lweziphumo ze-cerebral bleeding, umonakalo wobuchopho kunye ne-progressive muscular atrophy, ngokungena kumqobo wegazi-ingqondo (ukungena kwamanzi kumalunga nama-65%), ukukhuthaza ukulungiswa kwe-nerve cell membrane kunye nokuhlaziywa kwenkqubo yemithambo-luvo, kunye nokuphucula isantya sokuhanjiswa kwemithambo-luvo.
(3) Izifo zeMetabolic: Kunyango lwe-hepatitis kunye ne-cirrhosis, i-ATP disodium inokunyusa umsebenzi we-mitochondrial wee-hepatocytes, ikhawulezise ukulungiswa kwe-hepatocyte, kwaye inciphise amanqanaba e-ALT kunye ne-AST; ikwanayo nefuthe lokuphucula elincedisayo kwiingxaki zeswekile (ezifana ne-peripheral neuropathy).
3. Iindawo ezisakhulayo zokufaka izicelo
(1) Inkqubo yokuhambisa amayeza ekujoliswe kuyo: I-ATP disodium ingasetyenziswa njengesiguquli sokuthwala, idityaniswe ne-liposomes okanye ii-nanoparticles, ukufezekisa ukuhanjiswa kwamayeza ekujoliswe kuwo nge-endocytosis elawulwa yi-receptor. Umzekelo, kunyango lwe-tumor, ii-nanomedicines eziguqulwe yi-ATP zinokuphucula ukusebenza kakuhle kokubulala amayeza e-chemotherapy kwiiseli zomhlaza.
(2) Inkcubeko yeeseli kunye ne-biopharmaceuticals: Njengenxalenye ephambili yenkcubeko yeeseli, i-ATP disodium inokukhuthaza ukukhula kunye nokubonakaliswa kweeproteni zeeseli ze-CHO, iiseli ze-HEK293, njl.njl., kwaye isetyenziswa kakhulu kwimveliso ye-antibody ye-monoclonal.