2-Iminothiolane CAS 4781-83-3

I-CAS:4781-83-3

Ifomula yeMolekyuli:C6H14NNaO3S3

Ubunyulu:≥95%

Ubunzima beemolekyuli:267.35

Isithethantonye:I-2-Iminothiolane,98%;2-Iminothiolane hydrochloride,2-Thiolanimine hydrochloride,2IT,Dihydro-2(3H)-thiophenimine hydrochloride, i-reagent yeTraut

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Khuphela

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Yintoni i-2-Iminothiolane CAS 4781-83-3?

I-2-Iminothiolane ngumgubo omhlophe ukuya kongwevu-mhlophe kwaye yi-thiolating reagent ye-primary amines. Xa i-pH iphakathi kwe-7 kunye ne-10, i-amidine bond iyasabela ukwenza amaqela e-free thiol. I-2-Iminothiolane isetyenziselwa ukulungiselela i-disulfide kunye/okanye i-sulfide bond conjugates.

Inkcazo

INTO	UMGANGATHO
Inkangeleko	Iikristale ezimhlophe
Ubunyulu	≥95%
Amanzi	≤1%

Isicelo

1. Ukuguqulwa kwe-biomolecular thiolation: Njenge-reagent ye-thiolation, i-2-iminothiane hydrochloride inokusabela ngokukodwa namaqela e-amino aphambili kwi-biomolecules ezifana neeproteni, iipeptides, kunye neepolysaccharides phantsi kweemeko ze-pH ze-7-9, ize ingenise amaqela e-thiol. Le nkqubo ayiboneleli nje kuphela ngeendawo ezintsha ezisebenzayo ze-biomolecules kodwa ikwagcina iipropati zetshaja zamaqela e-amino okuqala, nto leyo enceda ekuguqulweni kokusebenza okulandelayo.

2. Ukudibanisa kunye nokudibanisa i-biomolecular: Amaqela e-thiol angenisiweyo angasetyenziselwa ukulungiselela ii-conjugates ezidityaniswe yi-disulfide okanye ii-thioether bonds, ukufezekisa ukudibana phakathi kwe-biomolecules. Umzekelo, kuphando lwe-proteomics, i-2-Iminothiolane ingasetyenziselwa ukulebhelisha iipeptide kunye nophando lokunxibelelana kwe-biomolecular, kunye nokudibanisa i-RNA-protein, okunceda ekuphononongweni okunzulu kobudlelwane besakhiwo kunye nokusebenza kwe-biomolecules.