I-Tolfenamic acid CAS 13710-19-5

I-CAS:13710-19-5

Ifomula yemolekyuli:I-C14H12ClNO2

Ubunzima beMolekyuli:261.7

EINECS:237-264-3

Izithethantonye:I-LABOTEST-BB LT00772313; I-TOLFENAMIC ACID; I-2-((3-chloro-2-methylphenyl)amino)-benzoicaci;n-(2-methyl-3-chlorophenyl)anthranilicacid; 2-(3-CHLORO-O-TOLUIDINO)BENZOIC ACID; 2 (3-CHLORO-2-METHYLANILINO)BENZOIC ACID; 2-[(3-CHLORO-2-METHYLPHENYL)AMINO]BENZOIC ACID; iTolfidine; 2-[(3-Chloro-o-tolyl)amino]benzoic acid; n-(3-chloro-o-tolyl)-anthranilicaci; I-CLOTAM; n-(3-chloro-o-tolyl) -anthranilicacid

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Yintoni i-Tolfenamic acid CAS 13710-19-5?

I-Tolfenamic acid lichiza elichasene nokudumba elingeyo-steroidal elisetyenziswa ngokubanzi kwiiklinikhi njengeyeza elichasayo, elithomalalisa iintlungu, kunye nelokudumba. Iphuma kwi-ortho aminobenzoic acid, i-Tolfenamic acid, ephuhliswe yi-GEA eDenmark. Ineempembelelo ezinamandla ezichasayo kunye ne-analgesic ezineziphumo ebezingalindelekanga ezincinci.

Inkcazo

Into	Inkcazo
Indawo yokubilisa	405.4±40.0 °C(Kuqikelelwe)
Ukuxinana	1.2037 (uqikelelo olurhabaxa)
MW	261.7
pKa	3.66±0.36(Kuqikelelwe)
EINECS	223-123-3
Indawo yokubilisa	405.4±40.0 °C(Kuqikelelwe)

Isicelo

I-asidi ye-Tolfenamic isebenzisa i-antipyretic kunye ne-analgesic effect ngokuthintela ukuveliswa kwe-cyclooxygenase. Okwangoku, isetyenziswa kakhulu kunyango lwezifo ezifana ne-rheumatoid arthritis kunye ne-migraine ekusebenzeni kweklinikhi. Kwiminyaka yakutshanje, abaphengululi ekhaya nakwamanye amazwe baye baqhuba izifundo ezahlukeneyo kule nto kwaye bafumanisa ukuba i-Tolfenamic acid idlala indima ebalulekileyo ekuthinteleni ukukhula kweseli ye-tumor, ilawula i-apoptosis yeseli ye-tumor, iphazamise ukubonakaliswa kweseli ye-tumor, ilawula umsebenzi we-oncogenes kunye ne-tumor suppressor genes, kunye nokuthintela i-angiogenesis ye-tumor.