I-Sodium Stearyl Fumarate CAS 4070-80-8

I-CAS:4070-80-8

Ifomula yeemolekyuli:C22H41NaO4

Ubunzima beMolekyuli:392.56

EINECS:223-781-1

Izithethantonye:ityuwa yesodium;SODIUMMONO-STEARYLFUMARATE;Isodium stearyl 2-fumarate;iSodium stearyi fumarate;SODIUM STEARYL FUMARATE;sodium octadecyl fumarate

Shiya uMyalezo Wakho

Iinkcukacha zeMveliso

Khuphela

Iithegi zeMveliso

Yintoni iSodium Stearyl Fumarate CAS 4070-80-8?

I-Sodium Stearyl Fumarate ngumgubo omhlophe ococekileyo. Inyibilika kwi-methanol, phantse ayinyibiliki emanzini. I-Sodium Stearyl Fumarate ifunyanwa ngokusabela kwi-alcohol ye-stearic kunye ne-anhydride ye-maleic, i-isomerizing imveliso yokusabela ibe yityuwa. I-Sodium Stearyl Fumarate sisithambisi se-hydrophilic esisetyenziswa njenge-lubricant kwi-excipients zamayeza. Inokoyisa iingxaki ezininzi ezinxulumene ne-magnesium stearate, njengokuchaphazela ichiza eliphambili kunye nokuthambisa okugqithisileyo; Ukwenza ifilimu ekhuselayo kwiipilisi ezisebenzayo kunokuphucula ukuhlukana, ukukhuthaza ukuchithwa, kwaye ngaloo ndlela kwandise i-bioavailability.

Inkcazo

Into	Inkcazo
Indawo yokunyibilika	>196°C (ngoDisemba)
Iimeko zokugcina	Umoya ophantsi, uBubushushu beGumbi
ubunyulu	98%
LogP	8.789 (est)
umbala	Mhlophe ukuya kumhlophe

Isicelo

I-sodium stearate fumarate (C22H39NaO4) yinto esetyenziswa ngokubanzi kwaye ibalulekile kwiyeza kunye nokutya okuphumayo. Ngexesha lenkqubo ye-metabolic ye-sodium fumarate kwizilwanyana, uninzi lwayo lunokufunxwa kwaye lufakwe nge-hydrolyzed ukuvelisa utywala obunxilisayo kunye ne-stearic acid. Inxalenye encinci inokuthe ngqo kwaye ikhawuleze i-metabolized, kwaye ayinayo ityhefu kwaye ayicaphukisi. Kwintsimi yamachiza, i-sodium stearate fumarate yongezwa kwimixube yeziyobisi njenge-lubricant yeepilisi kunye nee-capsules. I-Chemicalbook inokwenza ifilimu ekhuselayo kwiipilisi ezisebenzayo, ezinokusombulula iingxaki ze-lubricant stearate kunye nokuphucula ukuchithwa kweziyobisi kunye nokukhuthaza ukuchithwa kweziyobisi. Kwishishini lokutya, i-FDA ivumela i-sodium fumarate stearate ukuba yongezwe ngokuthe ngqo njengomlawuli kunye nokuzinzisa ekutyeni okulungiselelwe ukutyiwa ngabantu, njengezinto ezahlukeneyo ezibhakiweyo, ukutya okutyetyisiweyo komgubo, iitapile ezomisiweyo, kunye neenkozo ezicutshungulweyo. Isixa se-sodium fumarate eyongeziweyo sinokuphendula kwi-0.2-1.0% yobunzima bokutya.