SHIKONIN CAS 517-89-5 Shikonine

CAS:517-89-5

izithethantonye:

5,8-Dihydroxy-2-[(R) -1-hydroxy-4-methyl-3-pentenyl] -1,4-naphthalenedione;TokyoViolet;(R) -5,8-Dihydroxy-2-(1-hydroxy -4-Methylpent-3-en-1-yl)naphthalene-1,4Chemicalbook-dione;SHIKONIN(AS);Shikonin,froMArnebiasp.;(-)-ShikoninChina;Shikonine;Shikonin5,8-Dihydroxy-2-[(1R) )-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione

Igama leBrand: Unilong
Indawo yemvelaphi: Shandong, China
Ubunyulu:99%

Igama lemveliso:SHIKONIN

Ukupakisha: 25kgs / igubu

Ukuhanjiswa:Ngoko nangoko

MF:C16H16O5

MW:288.3

Shiya uMyalezo Wakho

Iinkcukacha zeMveliso

Khuphela

Iithegi zeMveliso

Yintoni iSHIKONIN

Ikristale yenaliti emfusa-mdaka, indawo yokunyibilika 147℃, ukujikeleza kwamehlo αD20=+135°(benzene). I-soluble kwi-phenethyl ether, i-acetone, i-chloroform, i-methanol, i-ethanol, i-glycerol, i-oyile yezilwanyana kunye nemifuno kunye nezisombululo ze-alkaline ezinamanzi, ezinganyibilikiyo emanzini. I-hue itshintsha ngexabiso le-Ph, ngexabiso le-Ph lika-4-6 libomvu, ixabiso le-Ph lika-8 limfusa, kwaye ixabiso le-Ph lika-10-12 liluhlaza okwesibhakabhaka. Ukumelana nokukhanya okulungileyo, ukumelana nobushushu kunye nokumelana ne-oxidation, ukungazinzi ekunciphiseni umthamo, kunye nombala omfusa obumnyama kwimeko ye-iron ion. Unempembelelo ethile ye-antibacterial.

Inkcazo yeSHIKONIN

CAS	517-89-5
Amanye Amagama	Shikonine
Imbonakalo	umgubo omfusa
Ubunyulu	99%
Umbala	mfusa
Ugcino	Ugcino olomileyo olupholileyo
Iphakheji	25kg/ibhegi
Isicelo	Ukutya

Ukusetyenziswa kweSHIKONIN

(1) Impembelelo ye-Hypoglycemic Isicatshulwa seqabunga se-comfrey kunye ne-polysaccharide (A, B, C) ye-comfrey inomphumela ocacileyo we-hypoglycemic.

(2) Impembelelo ye-Bacteriostatic Lithospermum ine-inhibitory effect kwi-Jingke 68-1 virus in vitro, kwaye ine-inhibitory effect kwi-Staphylococcus aureus. Impembelelo yentsholongwane ye-anti-parainfluenza ye-levoshikonin yafundwa yi-hemagglutination reaction kunye nendlela ye-cytopathic. Iziphumo zabonisa ukuba yayinetyhefu esezantsi kuluhlu loxinaniso olusetyenzisiweyo kuvavanyo, kwaye yayinomsebenzi othile we-in vitro anti-influenza virus kunye nokubulawa ngokuthe ngqo kwentsholongwane ye-parainfluenza. isiphumo.

(3) Iimpembelelo kwi-blood coagulation: I-injection ye-intraperitoneal yamacandelo e-shikonin (i-shikonin, i-acetylshikonin) ayichaphazeli ixesha le-coagulation yegazi, kodwa inokuthintela umphumo we-anticoagulant we-heparin.

(4) Impembelelo ye-Anti-tumor Isicatshulwa seComfrey sinempembelelo ethile yokuthintela kwinqanaba lokugqibela (isigaba se-G2) se-DNA synthesis kwiiseli ze-Hela.

(5) Impembelelo ye-Antitumor i-Shikonin inqanda ukwanda, ikhuthaza i-apoptosis kwaye ibangela ukubanjwa kwe-cell cycle kubanjwe kwi-culture ye-choriocarcinoma ye-cell-resistant cell lines (JAR / MTX) kwi-vitro. Iimvavanyo zibonisa ukuba ukuxinwa kwe-shikonin kuyanda kunye nedosi. Kwaye ukwanda kwexesha lesenzo, izinga lokuthintela ukukhula kweeseli ze-choriocarcinoma ezinganyangekiyo ngamachiza nalo landa kakhulu.

(6) Iziphumo zokukhuselwa kwehomoni Isiphumo se-shikonin kumsebenzi we-hypothalamic-pituitary-gonadal axis kwiimpuku zasetyhini ezifikisayo zibonise ukuba amanqanaba e-serum hormone kwiqela le-shikonin ayephantsi kakhulu kunalawo akwiqela elibi lolawulo, kwaye kwakukho. akukho mahluko ubalulekileyo xa kuthelekiswa neqela elilungileyo lolawulo. ezahlukeneyo. Ibonisa ukuba i-shikonin inokuthintela umsebenzi we-hypothalamic-pituitary-gonadal axis kwiigundane.

(7) Impembelelo ye-Antioxidant Abanye abaphandi balinganisa amandla okucoca i-shikonin kwi-superoxide radical (O2-) kunye ne-1,1-diphenyl-2-picrophenhydrazine radical (DPPH), kunye nefuthe layo kwi-β- - Inhibition ye-carotene / linoleic acid autoxidation inkqubo. Iziphumo zibonise ukuba i-shikonin inamandla okukhupha i-DPPH kunye ne-O2-, kwaye yayinempembelelo ecacileyo yokuthintela kwinkqubo ye-auto-oxidation ye-β-carotene / linoleic acid. Umthamo onamandla we-antioxidant.