SHIKONIN CAS 517-89-5 Shikonine

I-CAS: 517-89-5

amagama afanayo：

5,8-Dihydroxy-2-[(R)-1-hydroxy-4-methyl-3-pentenyl]-1,4-naphthalenedione;TokyoViolet;(R)-5,8-Dihydroxy-2-(1-hydroxy-4-Methylpent-3-en-1-yl)naphthalene-1,4Chemicalbook-dione;SHIKONIN(AS);Shikonin,froMAarnebiasp.;(-)-ShikoninChina;Shikonin;Shikonin5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione

Igama leBrand: Unilong
Indawo yokuQala: Shandong, China
Ubumsulwa: 99%

Igama lemveliso: SHIKONIN

Ukupakisha: 25kgs/igubu

Ukuhanjiswa: Kwangoko

MF:C16H16O5

MW:288.3

Shiya umyalezo wakho

Iinkcukacha zeMveliso

Khuphela

Iithegi zeMveliso

Yintoni iSHIKONIN

Ikristale yenaliti emfusa-mdaka, indawo yokunyibilika eyi-147℃, ukujikeleza okubonakalayo αD20=+135°(benzene). Inyibilika kwi-phenethyl ether, i-acetone, i-chloroform, i-methanol, i-ethanol, i-glycerol, iioyile zezilwanyana nemifuno kunye nezisombululo zamanzi ze-alkaline, azinyibiliki emanzini. Umbala uyatshintsha ngexabiso le-Ph, kunye nexabiso le-Ph eliyi-4-6 elibomvu, ixabiso le-Ph eliyi-8 elimfusa, kunye nexabiso le-Ph eliyi-10-12 eliluhlaza okwesibhakabhaka. Ukumelana kakuhle kokukhanya, ukumelana nobushushu kunye nokumelana ne-oxidation, ukungaguquguquki kwidosi encitshisiweyo, kunye nomthubi omnyama xa kukho ii-ion zesinyithi. Inefuthe elithile lokulwa neentsholongwane.

Inkcazo yeSHIKONIN

I-CAS	517-89-5
Amanye Amagama	I-Shikonine
Inkangeleko	umgubo omfusa
Ubunyulu	99%
Umbala	mfusa
Indawo yokugcina izinto	Indawo yokugcina epholileyo neyomileyo
Iphakheji	25kg/ibhegi
Isicelo	Ukutya

Ukusetyenziswa kweSHIKONIN

(1) Isiphumo se-Hypoglycemic Isicatshulwa segqabi le-comfrey kunye ne-polysaccharide (A, B, C) ye-comfrey zinomphumo ocacileyo we-hypoglycemic.

(2) Isiphumo seBacteriostatic I-Lithospermum inesiphumo sokuthintela intsholongwane yeJingke 68-1 kwi-vitro, kwaye inesiphumo sokuthintela i-Staphylococcus aureus. Isiphumo sentsholongwane ye-levoshikonin yokulwa ne-parainfluenza sifundwe nge-hemagglutination reaction kunye ne-cytopathic method. Iziphumo zibonise ukuba inetyhefu ephantsi ngaphakathi koluhlu loxinzelelo olusetyenzisiweyo kuvavanyo, kwaye inesiphumo esithile sokulwa nentsholongwane ye-influenza kwi-vitro kunye nokubulawa ngokuthe ngqo kwentsholongwane ye-parainfluenza.

(3) Iziphumo ekujikeni kwegazi: Ukufakwa kwe-intraperitoneal kwezinto ze-shikonin (shikonin, acetylshikonin) akuchaphazeli ixesha lokujiya kwegazi, kodwa kunokuthintela isiphumo se-heparin sokujiya kwegazi.

(4) Isiphumo sokulwa nomhlaza I-Comfrey extract inefuthe elithile lokuthintela kwinqanaba lokugqibela (isigaba se-G2) sokwenziwa kwe-DNA kwiiseli zeHela.

(5) Isiphumo sokulwa nethumba iShikonin ithintela ukwanda, ikhuthaza i-apoptosis kwaye ibangela ukubanjwa komjikelo weseli kwimigca yeeseli ezichasene namayeza e-choriocarcinoma (JAR/MTX) ezikhuliswe kwi-vitro. Uvavanyo lubonisa ukuba uxinaniso lwe-shikonin luyanda ngedosi. Kwaye ukolulwa kwexesha lokusebenza, izinga lokuthintela ukukhula kweeseli ezichasene namayeza e-choriocarcinoma nalo landa kakhulu.

(6) Iziphumo ekukhutshweni kwehomoni Isiphumo se-shikonin ekusebenzeni kwe-hypothalamic-pituitary-gonadal axis kwiimpuku zabasetyhini abaselula sibonise ukuba amanqanaba ehomoni ye-serum kwiqela le-shikonin ayephantsi kakhulu kunalawo akwiqela lolawulo olubi, kwaye bekungekho mahluko ubalulekileyo xa kuthelekiswa neqela lolawulo oluhle. Ibonisa ukuba i-shikonin inokuthintela ukusebenza kwe-hypothalamic-pituitary-gonadal axis kwiimpuku.

(7) Isiphumo se-Antioxidant Abanye abaphandi balinganise amandla okucola e-shikonin kwi-superoxide radical (O2-) kunye ne-1,1-diphenyl-2-picrophenhydrazine radical (DPPH), kunye nesiphumo sayo kwi-β- - Inhibition yenkqubo ye-carotene/linoleic acid autoxidation. Iziphumo zibonise ukuba i-shikonin inamandla okucola e-DPPH kunye ne-O2-, kwaye inesiphumo esicacileyo sokuthintela kwinkqubo ye-auto-oxidation ye-β-carotene/linoleic acid. Amandla e-antioxidant aqinileyo.