Rifamycin S CAS 13553-79-2

I-CAS:13553-79-2

Ifomula yeemolekyuli:C37H45NO12

Ubunzima beMolekyuli:2695.75

EINECS:236-938-4

Izithethantonye:Ukungcola kwe-Rifaximin E (EP); I-Rifaximin Ukungcola 5 (Rifaximin EP Ukungcola E); I-Rifamycin, i-1,4-dideoxy-1,4-dihydro-1,4-dioxo-; Rifaximin EP Ukungcola E; rifamycin; Rifamycin S CRS; Ukungacoceki kwe-Rifamycin 2(Rifamycin EP Ukungcola B) (Rifamycin S); Rifamycin S USP/EP/BP

Shiya uMyalezo Wakho

Iinkcukacha zeMveliso

Khuphela

Iithegi zeMveliso

Yintoni i-Rifamycin S CAS 13553-79-2?

I-Rifamycin S yimveliso yesizukulwana sesithathu sodidi lwamachiza e-rifampicin, anokusebenza okuphezulu kunye nomsebenzi wokulwa neentsholongwane ezibanzi. Inovakalelo oluphezulu kwiibhaktheriya ezahlukeneyo ezixhaphakileyo ngokwezonyango. I-Lipomycin B ingena kwi-oxidation, ukunciphisa, kunye ne-hydrolysis ukuvelisa i-rifampicin sodium.

Inkcazo

Into	Inkcazo
Indawo yokubilisa	700.89°C (uqikelelo olurhabaxa)
Ukuxinana	1.2387 (uqikelelo olurhabaxa)
Indawo yokunyibilika	179-181°C (dec.)
pKa	3.85±0.70(Kuqikelelwe)
ukumelana	1.6630 (uqikelelo)
Iimeko zokugcina	-20°C Isikhenkcisi

Isicelo

I-Rifamycin S isetyenziswa njenge-pharmaceutical intermediate ukuthintela umsebenzi we-bacterial RNA polymerase. Ukuthintela ukuhlanganiswa kwe-RNA yebhaktheriya, ekugqibeleni kuthintele ukuhlanganiswa kweeprotheni ezifunwa yibhaktheriya, okukhokelela ekufeni kwebhaktheriya kunye nokubonisa imiphumo ye-bactericidal.