REVERSE T3 CAS 5817-39-0

I-CAS:5817-39-0

Ifomula yemolekyuli:C15H12I3NO4

Ubunzima beMolekyuli:650.97

EINECS:621-265-4

Izithethantonye:Reverse triiodothyronine; triiodothyronine, umva; I-TRIIODOTHYRONINE; 3,3′,5′-Triiodo-L-thyronine 3,3′,5′-Triiodo-L-thyronine; 3,3′,5′-Triiodo-L-thyronine ye-thyroid horMone analog; O-(4-hydroxy-3,5-diiodophenyl) -3-iodo-L-Tyrosine; Levothyroxine EP Imp K; 3, 3', 5'- Triiodothyronine (Isisombululo); I-Triiodothyronine (L-Liothyronine; Reverse Triiodothyronine hydrochloride (Reverse T3)

Shiya uMyalezo Wakho

Iinkcukacha zeMveliso

Khuphela

Iithegi zeMveliso

Yintoni i-REVERSE T3 CAS 5817-39-0?

I-REVERSE T3, ekwabizwa ngokuba yi-anti rT3, yenziwa ngokuchithwa kwe-loop yangaphakathi ye-T4 (i-loop yangaphandle ye-T4 iguqulelwa kwi-T3). Phantse yonke (i-97%) ye-rT3 kwi-serum iguqulwa kwi-T4 kwizicubu ze-peripheral, kwaye malunga ne-50% ye-T4 efihliweyo yi-thyroid gland i-deiodinated ukuvelisa i-rT3; Malunga ne-3% ivela kwi-thyroid secretion.

Inkcazo

Into	Inkcazo
MW	650.97
Ukuxinana	2.387±0.06 g/cm3(Kuxelwe kwangaphambili)
Indawo yokunyibilika	234-238 °C(lit.)
pKa	2.17±0.20(Kuqikelelwe)
Iimeko zokugcina	Gcina kwindawo emnyama

Isicelo

I-REVERSE T3 inokugcina imisebenzi ye-physiological efana ne-metabolism, ukukhula kunye nokulawulwa kophuhliso, kwaye isetyenziswa kakhulu kwikliniki ukunyanga izifo ze-thyroid kunye nokulawula umsebenzi we-cardiovascular function.