iindaba

I-Hyaluronic acid yi-polysaccharide enkulu yemolekyuli ethathwe kwi-bovine vitreous humor ngooprofesa be-ophthalmology kwiYunivesithi yaseColumbia uMeyer noPalmer ngo-1934. Isisombululo sayo samanzi sicacile kwaye sinjengeglasi. Kamva, kwafunyaniswa ukuba i-hyaluronic acid yenye yezona zinto ziphambili kwi-human extracellular matrix kunye ne-intercellular matrix, kunye ne-filler phakathi kweeseli, idlala indima ebalulekileyo kwi-morphology, ulwakhiwo, kunye nomsebenzi wolusu. Ukwaluphala, imibimbi, kunye nokuwa komzimba womntu kunxulumene kakhulu nokwehla komxholo we-hyaluronic acid eluswini.

Ngokwesakhiwo, i-hyaluronic acid kukuxinana kwezinto ezimbini eziphuma kwiglucose, kwaye ngokuphinda-phinda olu lwakhiwo, iba yi-hyaluronic acid. Oku kufana kakhulu nolwakhiwo lweepolysaccharides ezininzi, ngoko ke i-sodium hyaluronateinomsebenzi ofanayo noweepolysaccharides ezininzi – ukufumisa.

Kodwai-hyaluronic acidayizinzanga. Ngokubanzi, i-hyaluronic acid ikhona kwimo yayo yetyuwa yesodiyam. Ngokwee-molecular weights ezahlukeneyo, i-hyaluronic acid inokwahlulwa ibe zii-molecular weight eziphezulu, i-medium molecular weight ephakathi, i-low molecular weight, kunye ne-oligomeric hyaluronic acid. Ngokukodwa, umenzi ngamnye unohlobo olufanayo lobunzima bee-molecular be-sodium hyaluronate.I-UNILONGngumvelisi wobungcali we-sodium hyaluronate, kubandakanya ibakala lokuhombisa, ibakala lokutya, i-sodium hyaluronate yenqanaba leyeza kunye nezinyei-sodium hyaluronateI-UNILONG ihlela i-sodium hyaluronate ngolu hlobo lulandelayo:

◆I-asidi ye-hyaluronic enobunzima obuphezulu beemolekyuli: I-asidi ye-hyaluronic inobunzima beemolekyuli obungaphezulu kwe-1500KDa, enokwenza ifilimu enokuphefumlwa phezu kolusu, ivale umswakama phezu kolusu, ithintele ukufuma komswakama, kwaye inike ukufuma ixesha elide. Kodwa ayinayo ingenelo imbi kwaye ayizukufunxwa lusu.

◆ I-asidi ye-hyaluronic enobunzima obuphakathi bemolekyuli: I-asidi ye-hyaluronic inobunzima bemolekyuli obuphakathi kwe-800KDa kunye ne-1500KDa kwaye inokwenza ifilimu enokuphefumlwa phezu kolusu, ivale umswakama kwaye iqinise ulusu.

◆I-asidi ye-hyaluronic enobunzima obuphantsi bemolekyuli: I-asidi ye-hyaluronic inobunzima bemolekyuli obuphakathi kwe-10KDa kunye ne-800KDa kwaye inokungena kumaleko we-dermis yolusu. Idlala indima ngaphakathi kolusu, ivale umswakama, ikhuthaza imetabolism yolusu, kwaye yenza ulusu lube manzi, lugudileyo, lube buthathaka, luthambile, kwaye lube nolusu oluthambileyo. Amandla okuthintela ukufuma kwamanzi aphantsi.

◆ I-Oligo hyaluronic acid: Iimolekyuli ze-Hyaluronic acid ezinobunzima beemolekyuli ezingaphantsi kwe-10KDa, oko kukuthi, izakhiwo ze-monosaccharide ezingaphantsi kwama-50 kunye ne-polymerization engaphantsi kwama-25, zinokungena nzulu kwi-dermis layer kwaye zisebenzise imiphumo yokufumisa ebanzi nehlala ihleli. Ngokungafaniyo neemolekyuli ze-hyaluronic acid eziqhelekileyo ezinemiphumo yokufumisa kumphezulu wesikhumba, zinexesha elide lokufumisa, iziphumo ezilungileyo, ukusetyenziswa ixesha elide, ukulwa nokwaluphala, kunye nemiphumo yokususa imibimbi.

Ezinye ii-asidi ze-hyaluronic zinokutshintshwa kwisakhiwo (i-acetylation, njl.njl.) ukuze zibe nobuhlobo ngakumbi nolusu. Ii-asidi ze-hyaluronic eziqhelekileyo ziyanyibilika emanzini, kodwa ukunamathela kwazo kulusu akwanelanga. Emva kokutshintshwa, zinokunamathela kakuhle kulusu.

Ukuba unemibuzo okanye iimfuno malunga ne-sodium hyaluronate, nceda uzive ukhululekile ukubuzanxibelelana ne-Unilongnangaliphi ixesha.