iindaba

Usenokuba unolwazi oluncinci nge-kojic acid, kodwa i-kojic acid inamalungu osapho, afana ne-kojic dipalmitate. I-Kojic acid dipalmitate yeyona arhente idumileyo yokwenza mhlophe i-kojic acid kwimarike okwangoku. Ngaphambi kokuba sazi i-kojic acid dipalmitate, masiqale sifunde nge-predecessor yayo – “kojic acid”.
I-Kojic Acidiveliswa ngokubiliswa kunye nokucocwa kweglucose okanye i-sucrose phantsi kwesenzo se-kojise. Indlela yayo yokwenza mhlophe kukuthintela umsebenzi we-tyrosinase, ukuthintela umsebenzi we-N-hydroxyindole acid (DHICA) oxidase, kunye nokuthintela i-polymerization ye-dihydroxyindole (DHI). Yiarhente enye engaqhelekanga yokwenza mhlophe enokuthintela ii-enzymes ezininzi ngexesha elinye.

Kodwa i-kojic acid inokukhanya, ubushushu kunye nokungazinzi kwe-ion yesinyithi, kwaye akulula ukuyifunxa lusu, ngoko ke kwavela i-kojic acid derivatives. Abaphandi baye baphuhlisa i-kojic acid derivatives ezininzi ukuphucula ukusebenza kwe-kojic acid. I-Kojic acid derivatives ayinayo nje kuphela indlela yokwenza mhlophe njenge-kojic acid, kodwa ikwasebenza ngcono kune-kojic acid.
Emva kokwenziwa kwe-ester nge-kojic acid, i-monoester ye-kojic acid inokwenziwa, kwaye i-diester nayo inokwenziwa. Okwangoku, i-arhente ye-kojic acid whitening edumileyo kwimarike yi-kojic acid dipalmitate (KAD), eyi-diesterified derivative ye-kojic acid. Uphando lubonisa ukuba isiphumo se-KAD whitening esidityaniswe ne-glucosamine derivatives siya kwanda ngokukhawuleza.

Ukusebenza kakuhle kokhathalelo lolusu lwe-kojic dipalmitate
1) Ukumhlophe: I-Kojic acid dipalmitate isebenza ngcono kune-kojic acid ekuthinteleni umsebenzi we-tyrosinase eluswini, ngaloo ndlela ithintela ukwakheka kwe-melanin, enefuthe elihle ekwenzeni mhlophe ulusu kunye ne-sunscreen.
2) Ukususwa kwamabala: I-Kojic acid dipalmitate inokuphucula umbala wesikhumba, kwaye inokulwa namabala obudala, amanqaku okunwebeka, amabala kunye nombala ngokubanzi.

Isikhokelo sokudibanisa izinto zobuhle zeDipalmitate
I-Kojic acid dipalmitateKunzima ukongeza kwifomyula kwaye kulula ukwenza i-crystal precipitation. Ukuze kusonjululwe le ngxaki, kucetyiswa ukongeza i-isopropyl palmitate okanye i-isopropyl myristate kwi-oil phase equlethe i-kojic dipalmitate, ufudumale i-oil phase ukuya kuma-80 ℃, ubambe imizuzu emi-5 de i-kojic dipalmitate ichitheke ngokupheleleyo, uze wongeze i-oil phase kwi-water phase, kwaye uyixube malunga nemizuzu eli-10. Ngokubanzi, ixabiso le-pH yemveliso yokugqibela efunyenweyo limalunga ne-5.0-8.0.
Umlinganiselo ocetyiswayo we-kojic dipalmitate kwizinto zokuthambisa yi-1-5%; Yongeza i-3-5% kwiimveliso zokwenza mhlophe.