Unokwazi okuncinci malunga ne-kojic acid, kodwa i-kojic acid inamanye amalungu entsapho, njenge-kojic dipalmitate. I-Kojic acid dipalmitate yeyona arhente idumileyo yokwenza mhlophe kwi-kojic acid kwimarike ngoku. Ngaphambi kokuba sazi i-kojic acid dipalmitate, masiqale sifunde malunga neyandulelayo - "i-kojic acid".
Kojic Acidiveliswa ngokuvutshelwa kunye nokucocwa kweglucose okanye i-sucrose phantsi kwesenzo sekojise. Indlela yayo emhlophe kukuthintela umsebenzi we-tyrosinase, ukuvimbela umsebenzi we-N-hydroxyindole acid (DHICA) oxidase, kunye nokuvimbela i-polymerization ye-dihydroxyindole (DHI). Yinto enqabileyo i-agent enye emhlophe enokuthintela i-enzymes ezininzi ngexesha elinye.
Kodwa i-asidi ye-kojic inokukhanya, ukushisa kunye nokungazinzi kwe-ion yensimbi, kwaye akukho lula ukufunxa ulusu, ngoko ke i-kojic acid derivatives yavela. Abaphandi baye baphuhlisa ezininzi i-kojic acid derivatives ukuphucula ukusebenza kwe-kojic acid. Izinto eziphuma kwi-asidi ye-Kojic azinayo nje indlela yokwenza mhlophe njenge-kojic acid, kodwa zisebenza ngcono kune-kojic acid.
Emva kwe-esterification kunye ne-kojic acid, i-monoester ye-kojic acid inokuqulunqwa, kwaye i-diester nayo inokwakheka. Okwangoku, eyona arhente idumileyo yokwenza mhlophe i-kojic acid kwimarike yi-kojic acid dipalmitate (KAD), eyi-diesterified derivative ye-kojic acid. Uphando lubonisa ukuba isiphumo sokwenza mhlophe kwe-KAD edityaniswe ne-glucosamine derivatives iya kwanda kakhulu.
Ukusebenza kokunyamekela kwesikhumba kwe-kojic dipalmitate
I-1) I-Whitening: I-Kojic acid dipalmitate iphumelele ngakumbi kune-asidi ye-kojic ekuvimbeleni umsebenzi we-tyrosinase kwesikhumba, ngaloo ndlela inqanda ukubunjwa kwe-melanin, enefuthe elihle kwisikhumba esimhlophe kunye ne-sunscreen.
I-2) Ukususwa kwe-Freckle: I-Kojic acid dipalmitate inokuphucula i-pigmentation yesikhumba, kwaye inokulwa namabala obudala, amanqaku alula, i-freckles kunye ne-pigmentation jikelele.
Isikhokelo seDipalmitate cosmetic compounding
Kojic acid dipalmitateKunzima ukongeza kwifomula kwaye kulula ukwenza i-crystal precipitation. Ukuze ucombulule le ngxaki, kuyacetyiswa ukuba udibanise isopropyl palmitate okanye isopropyl myristate kwisigaba seoli esiqulathe i-kojic dipalmitate, ukutshisa i-oyile ukuya kwi-80 ℃, ubambe imizuzu emi-5 de i-kojic dipalmitate inyibilike ngokupheleleyo, emva koko wongeze isigaba seoli. isigaba samanzi, kwaye u-emulsify malunga nemizuzu ye-10. Ngokuqhelekileyo, ixabiso le-pH lemveliso yokugqibela efunyenweyo malunga ne-5.0-8.0.
I-dosage ephakanyisiweyo ye-kojic dipalmitate kwi-cosmetics yi-1-5%; Yongeza i-3-5% kwiimveliso ezimhlophe.
Ixesha lokuposa: Oct-21-2022