I-Metronidazole CAS 443-48-1

Umfanekiso obonisiweyo weMetronidazole CAS 443-48-1

I-CAS:443-48-1

Ifomula yeMolekyuli:C6H9N3O3

Ubunzima beemolekyuli:171.15

I-EINECS:207-136-1

Izithethantonye:I-TIMTEC-BB SBB001486; 1-(2-Hydroxy-1-ethyl)-2-methyl-5-nitroimidazole; 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole; 1-(beta-Hydroxyethyl)-2-methyl-5-nitroimidazole; 1-(beta-Oxyethyl)-2-methyl-5-nitroimidazole; 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-; 1H-Imidazole-1-ethanol, 2-methyl-5-nitro-; 1-Hydroxyethyl-2-methyl-5-nitroimidazole; 2-(2-Methyl-5-nitro-1H-imidazole-1-yl)ethanol; 2-Methyl-1-(2-hydroxyethyl)-5-nitroimidazole

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Iinkcukacha zeMveliso

Khuphela

Iithegi zeMveliso

Yintoni iMetronidazole CAS 443-48-1?

I-Metronidazole yi-crystalline okanye i-crystalline powder emhlophe okanye etyheli kancinci; Kukho ivumba elincinci, elinencasa ekrakra nenetyuwa encinci. Inyibilika kancinci kwi-ethanol, inyibilika kancinci emanzini okanye kwi-chloroform, kwaye inyibilika kancinci kakhulu kwi-ether. I-Metronidazole yi-heterocyclic compound equlethe i-nitrogen ene-alkalinity kunye nokunyibilika kwamanzi okuphantsi. Ngokomgaqo we-prodrug, i-metronidazole yenziwa ibe yi-potassium phosphate ester, eyonyusa ukunyibilika kwayo emanzini kwaye ingasetyenziswa njengesisombululo se-injection.

Inkcazo

Into	Inkcazo
Indawo yokubila	301.12°C (uqikelelo oluqikelelweyo)
Uxinano	1.3994 (uqikelelo oluqikelelweyo)
Indawo yokunyibilika	159-161 °C (elikhanyayo)
i-pKa	i-pKa 2.62(H2O,t =25±0.2,
Iimeko zokugcina	2-8°C

Isicelo

I-Metronidazole inefuthe elinamandla lokulwa neentsholongwane kwiintsholongwane ezininzi ze-anaerobic kwaye isetyenziselwa ukunyanga i-amoebiasis, i-trichomoniasis, kunye nosulelo lwebhaktiriya ye-anaerobic. Ikwasetyenziselwa ukunyanga i-trichomoniasis yesini kwaye isetyenzisiwe kwi-amoebiasis yamathumbu nangaphandle kwamathumbu ukusukela ngo-1970. Ukusebenza kwayo kuphezulu, ubuthi buphantsi, kwaye isetyenziswa kakhulu. Inefuthe le-mutagenic kunye ne-teratogenic kwizilingo zezilwanyana.