I-Madecassic acid ene-CAS 18449-41-7

MF:C30H48O6

Ubunzima beemolekyuli:504.71

Inkangeleko:Umgubo

Isithethantonye:(2alpha,3beta,4alpha,6beta)-2,3,6,23-tetrahydroxy-urs-12-en-28-oicacid;MADECASSICACID;Urs-12-en-28-oicacid,2,3,6,23-tetrahydroxy-,(2.alpha.,3.beta.,4.alpha.,6.beta.)-

Shiya umyalezo wakho

Iinkcukacha zeMveliso

Khuphela

Iithegi zeMveliso

Yintoni iMadecassic acid eneCAS 18449-41-7?

I-Madecassic acid yi-triterpenoid efunyenwe kwi-C. asiatica kwaye inemisebenzi eyahlukeneyo yebhayoloji. Ithintela ukuveliswa kwe-nitric oxide (NO) ebangelwa yi-LPS, i-prostaglandin E2 (PGE2; Inombolo yento 14010), i-TNF-α, i-IL-1β, kunye ne-IL-6 kwi-RAW 264.7 macrophages xa isetyenziswa kuxinzelelo lwe-150 μg/ml. I-Madecassic acid (0.05 kunye ne-0.1% ekutyeni) inciphisa amanqanaba e-plasma e-fibrinogenin kunye ne-triglycerides, kunye namanqanaba entliziyo kunye nezintso ze-reactive oxygen species (ROS), kwimodeli yegundane yesifo seswekile esibangelwa yi-streptozotocin (STZ; Inombolo yento 13104). Inciphisa ukukhula kwe-tumor kwimodeli yomhlaza we-murine colon ye-CT26 ngendlela exhomekeke kumthamo.

Inkcazo yeMadecassic acid eneCAS 18449-41-7

I-CAS	18449-41-7
Amagama	I-Madecassic acid
Inkangeleko	Umgubo
Ubunyulu	98%
MF	C30H48O6
Ibanga	Ukutya $ Ibanga lezonyango
Iphakheji	25kgs/ibhegi, iitoni ezingama-20/isikhongozeli esingama-20'
Igama lebrand	I-Unilong

Ukusetyenziswa kweMadecassic acid kunye neCAS 18449-41-7

I-Madecassic Acid yi-terpenoid ene-ursane skeleton ehlukanisiweyo neCentella asiatica. I-Madecassic Acid ibonisa iipropati zokulwa nokuvuvukala ngenxa ye-iNOS, i-COX-2, i-TNF-alpha, i-IL-1beta, kunye ne-IL-6 inhibition ngokunciphisa ukusebenza kwe-NF-kappaB kwiiseli ze-RAW 264.7 macrophage.