I-asidi ye-Madecassic kunye ne-CAS 18449-41-7

MF:C30H48O6

Ubunzima bemolekyuli:504.71

Imbonakalo:Umgubo

Isithethantonye:(2alpha,3beta,4alpha,6beta)-2,3,6,23-tetrahydroxy-urs-12-en-28-oicacid;MADECASSICACID;Urs-12-en-28-oicacid,2,3,6,23- tetrahydroxy-,(2.alpha.,3.beta.,4.alpha.,6.beta.)-

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Yintoni i-Madecassic acid kunye ne-CAS 18449-41-7?

I-Madecassic acid yi-triterpenoid efunyenwe kwi-C. asiatica kwaye inemisebenzi eyahlukeneyo yezinto eziphilayo. Ivimbela i-LPS-induced production ye-nitric oxide (NO), i-prostaglandin E2 (PGE2; Inqaku le-14010), i-TNF-α, i-IL-1β, kunye ne-IL-6 kwi-RAW 264.7 macrophages xa isetyenziswe kwi-concentration ye-150 μg / ml . I-Madecassic acid (i-0.05 kunye ne-0.1% ekudleni) iyanciphisa amanqanaba e-plasma ye-fibrinogenin kunye ne-triglycerides, kunye nentliziyo kunye nezintso zeentlobo ze-oxygen esebenzayo (ROS), kwimodeli yegundane yesifo sikashukela eyenziwa yi-streptozotocin (STZ; Inqaku le-13104). ). Iyanciphisa ukukhula kwethumba kwimodeli yomhlaza wekoloni ye-CT26 murine ngendlela exhomekeke kwidosi.

Ukucaciswa kwe-Madecassic acid kunye ne-CAS 18449-41-7

CAS	18449-41-7
Amagama	Madecassic acid
Imbonakalo	Umgubo
Ubunyulu	98%
MF	C30H48O6
IBanga	Ukutya $ Ibanga lezonyango
Iphakheji	25kgs/bag,20tons/20'container
Igama lebrand	Ubudenge

Ukusetyenziswa kwe-Madecassic acid kunye ne-CAS 18449-41-7

I-Madecassic Acid yi-terpenoid ene-ursane skeleton ekwanti kwi-Centella asiatica. I-Madecassic Acid ibonisa iipropati ezichasayo ngenxa ye-iNOS, i-COX-2, i-TNF-alpha, i-IL-1beta, kunye ne-IL-6 inhibition ngokusebenzisa ukulawulwa kwe-NF-kappaB yokusebenza kwi-RAW 264.7 iiseli ze-macrophage.