Cinchonine CAS 118-10-5

I-CAS:118-10-5

Ifomula yemolekyuli:I-C19H22N2O

Ubunzima beMolekyuli:294.39

EINECS:204-234-6

Izithethantonye:(+)-cinconine; (8r,9s)-cinchonine; (9s)-cinchonan-9-o; (9S)-Cinchonan-9-ol; (+)-CINCHONINE; I-CINCHONINE; CINCHONAN-9-OL,(9S)-; Cinchonine, 98+%; Cinchonine dihydrate monohydrochloride; I-Cinchonine Solution [yesitshizi]; (9S) -Cinconan-9-ol

Shiya uMyalezo Wakho

Iinkcukacha zeMveliso

Khuphela

Iithegi zeMveliso

Yintoni iCinchonine CAS 118-10-5?

I-Cinchonine luhlobo lwe-quinoline alkaloid, uhlobo lwe-alkaloid efumaneka kwi-cinchona alkaloids, eyaziwa ngokuba yi-cinchonine okanye i-cinchona alkaloids engenamandla. Yi-stereoisomer ye-cinchonidine. I-Xinken yi-alkaloid enomxholo ophezulu kwixolo le-cinchona bark, ngaphandle kwe-quinine.

Inkcazo

Into	Inkcazo
Iimeko zokugcina	Ubushushu beGumbi
Ukuxinana	1.0863 (uqikelelo olurhabaxa)
Indawo yokunyibilika	260-263 °C
pKa	5.85, 9.92(nge-25℃)
MW	294.39
Indawo yokubilisa	436.16°C (uqikelelo olurhabaxa)

Isicelo

Isiphumo seCinchonine ekukhuleni kweseli yethumba yaphandwa, kwaye kwafunyaniswa ukuba iCinchonine inokukhuthaza i-tumor cell apoptosis. Ezi ziphumo zovavanyo zingasentla zibonisa ukuba iCinchonine inokuthintela ukukhula kweeseli zethumba, ikhuthaze i-apoptosis yokuqala yamathumba, iphucule ukubonakaliswa kwezinto ze-apoptotic, kwaye inqanda ukubonakaliswa kwezinto ezichasene ne-apoptotic. I-Xinnkening kulindeleke ukuba isetyenziswe kwiindawo ezichasene ne-tumor kwixesha elizayo.