I-Celastrol CAS 34157-83-0

Umfanekiso obonisiweyo weCelastrol CAS 34157-83-0

I-CAS:34157-83-0

Ifomula yeMolekyuli:C29H38O4

Ubunzima beemolekyuli:450.61

I-EINECS:636-472-5

Izithethantonye:I-CELASTROL(SH); I-CELASTROL; I-Celastrol (iTripterin); I-CELASTROL(P)(NCEDA UFOWUNE); (20R)-3-Hydroxy-2-oxo-24-nor-D:A-friedoolean-1(10),3,5,7-tetren-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedela-1(10),3,5,7-tetraene-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedelane-1(10),3,5,7-tetraene-29-oic acidI-Celasterol

Shiya umyalezo wakho

Iinkcukacha zeMveliso

Khuphela

Iithegi zeMveliso

Yintoni iCelastrol CAS 34157-83-0?

I-Celastrol ayinyibiliki emanzini, inyibilika kwi-dimethyl sulfoxide kunye ne-anhydrous ethanol. Ivela kwizithako ezisebenzayo zokulwa nomhlaza kwizityalo ezifana neThunder God Vine kunye neSouth Snake Vine kusapho lweCelastraceae. I-proteasome inhibitor esebenzayo, iqinisekisiwe ukuba ibangela i-cancer cell apoptosis ngokuthintela umsebenzi we-proteasome.

Inkcazo

Into	Inkcazo
Indawo yokubila	645.7±55.0 °C (Kuqikelelwe)
Uxinano	1.2
Indawo yokunyibilika	219-230°C
i-pKa	4.78±0.70(Kuqikelelwe)
ubuninzi be-λ	424nm(MeOH)(elikhanyayo)
Iimeko zokugcina	-20°C

Isicelo

I-Celastrol isetyenziselwa ukumisela/ukuchonga/uvavanyo lweyeza, njl. Iziphumo zeyeza: Ineempawu ezinamandla ze-antioxidant, iziphumo ze-angiogenesis yomhlaza, kunye neziphumo ze-antirheumatoid. I-proteasome inhibitor esebenzayo, eqinisekisiweyo ukuba ibangela i-apoptosis yeeseli zomhlaza ngokuthintela umsebenzi we-proteasome.