ATP disodium ityuwa CAS 987-65-5

I-CAS:987-65-5

Ubunyulu:99%

Ifomula yemolekyuli:I-C10H17N5NaO13P3

Ubunzima beMolekyuli:531.18

EINECS:213-579-1

Ixesha loGcino:iminyaka eyi-2

Izithethantonye:ADENOSINETRIPHOSPHATEDISODIUM; I-ADENOSINETRIPHOSPHATE,DISODIUMSALT; I-ADENYLPYROPHOSPHORICACIDDISODIUMSALT; I-ADENOSINE-5′-TRIPHOSPHATEHYDRATEDISODIUMSALT; I-ADENOSINE-5′-TRIPHOSPHATENA2-YTYUWA; I-ADENOSINE-5′-TRIPHOSPHORICACID,DISODIUM; I-ADENOSINE-5′-TRIPHOSPHORICACIDDISODIUMDIHYDROGENSALT; I-ADENOSINE5′-TRIPHOSPHORICACIDDISODIUMSALT

Shiya uMyalezo Wakho

Iinkcukacha zeMveliso

Khuphela

Iithegi zeMveliso

Yintoni i-ATP disodium ityuwa CAS 987-65-5?

Ityuwa ye-ATP disodium yi-metabolite ye-adenosine, i-nucleoside triphosphate esebenzayo esetyenziswa njenge-coenzyme yokudluliselwa kwamandla e-intracellular kwiiseli. Ihambisa amandla ekhemikhali ngaphakathi kweeseli zemetabolism. Ityuwa ye-disodium ye-ATP isetyenziselwa ukudibanisa i-ribose-modified deoxyadenosine diphosphate analogs njenge-P2Y1 receptor ligands.

Inkcazo

Imbonakalo	Umgubo omhlophe okanye omhlophe-umgubo omhlophe okanye umgubo wekristale, onehygroscopic.
Ubungakanani besuntswana	＞I-95% idlula kwi-80 mesh.
pH	2.5–3.5
Ukunyibilika	Inyibilika emanzini; ayinyibilikiyo kwi-ethanol kunye ne-ether.
Oder	Ngaphandle kweOderless
Isiqulatho samanzi	6.0%~12.0%
I-chloride	≤0.05%
Ityuwa yentsimbi	≤0.001%
Iintsimbi ezinzima	≤0.001%
Inkokeli	≤2.0ppm
Arsenic	≤1.0ppm

Isicelo

1. Ukusetyenziswa kophando lweshishini kunye nesayensi
(1) Izinto ze-cosmetic ekrwada: zongezwa kwiimveliso zokhathalelo oluchasene nokuguga, inokuphucula ukuqina kolusu kunye nokuqaqamba ngokuvula i-metabolism yamandla eseli.
(2) Izongezo zokutya: ezisetyenziselwa ukunyusa ukondla kwiziphuzo zezemidlalo kunye nokutya okusebenzayo ukukhawuleza ukuzalisa amandla.
2. Iindawo zonyango lweklinikhi
(1) Izifo ze-cardiovascular system: isetyenziselwa ukuhluleka kwentliziyo, i-myocarditis, i-myocardial infarction kunye ne-cerebral arteriosclerosis, njl., ngokuphucula amandla e-myocardial metabolism kunye nokunciphisa i-coronary arteries (ukwandisa ukuhamba kwegazi malunga ne-30%), ukukhulula iimpawu ze-myocardial ischemia. Ngokomzekelo, kwizigulane ezine-acute myocardial infarction, i-ATP disodium inokunciphisa ixesha lokuwa kwecandelo le-ST kunye nokunciphisa ixabiso eliphezulu le-myocardial enzyme spectrum.
(2) Izifo ze-nervous system: unyango oluncedisayo lwe-sequelae ye-cerebral hemorrhage, umonakalo wobuchopho kunye ne-atrophy ye-muscular progressive, ngokungena kwi-barrier yegazi-brain barrier (i-permeability malunga ne-65%), ukukhuthaza ukulungiswa kwe-nerve cell membrane kunye nokuvuselelwa kwenkqubo ye-nerve, kunye nokuphucula i-nerve conduction velocity.
(3) Izifo ze-Metabolic: Kunyango lwe-hepatitis kunye ne-cirrhosis, i-ATP disodium inokunyusa umsebenzi we-mitochondrial we-hepatocytes, ukukhawuleza ukulungiswa kwe-hepatocyte, kunye nokunciphisa amanqanaba e-ALT kunye ne-AST; ikwanayo nempembelelo yokuphucula encedisayo kwiingxaki zesifo seswekile (ezifana ne-peripheral neuropathy).
3. Iindawo zezicelo ezivelayo
(1) Inkqubo yokunikezelwa kweziyobisi ezijoliswe kuyo: I-ATP disodium ingasetyenziselwa njenge-modifier ye-carrier, idibaniswe ne-liposomes okanye i-nanoparticles, ukuphumeza ukuhanjiswa kweziyobisi ezijoliswe kuyo nge-endocytosis ye-receptor-mediated. Ngokomzekelo, kunyango lwe-tumor, i-ATP-modified nanomedicines inokuphucula ukubulawa ngokufanelekileyo kwamachiza e-chemotherapy kwiiseli zomhlaza.
(2) Inkcubeko yeseli kunye ne-biopharmaceuticals: Njengenxalenye ephambili yenkcubeko yenkcubeko yeseli, i-ATP disodium inokukhuthaza ukukhula kunye nokubonakaliswa kweprotheni ye-CHO iiseli, iiseli ze-HEK293, njl., kwaye isetyenziswa ngokubanzi kwimveliso ye-antibody monoclonal.